CAT(Catalase) belongs to the catalase family. It is involved in catabolic pathway of activated oxygen species and free radical detoxification and the catalase overexpression has a protective role against UVB irradiation by preventing DNA damage mediated by the late ROS increase. Mammalian catalase of approximately 240 kD occurs as a complex of 4 identical subunits, each of which contains 526 amino acid residues(PMID:19122680). Defects in CAT are the cause of acatalasemia(ACATLAS). This antibody is specific to CAT.
Categories
Primary Antibodies
Clonality
polyclonal
Host
Rabbit
Immunogen
catalase
Isotype
IgG
Molecular Weight
60kd
Reactivity
Human
Regulatory
RUO
Antigen
Catalase-Specific
Uniprot
P04040
Gene Id
847
Research Area
Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)