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Home / Primary Antibodies / Polyclonal Antibodies

Caspase 8 antibody

SKU : BHA10801288

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Mfr.No.	FNab01293
Alternative Names	Apoptoticcysteineprotease ; ApoptoticproteaseMch5 ; Casp8 ; CASP8 ; Caspase8 ; Caspase8/p18 ; Caspase8 ; FADDlikeICE ; FLICE ; ICElikeapoptoticprotease5 ; MACH
Background	Caspase 8, also named as MCH5, MACH, FLICE, and CAP4, belongs to the peptidase C14A family. It may participate in the GZMB apoptotic pathways and functions as an upstream regulator in a-bisabolol-induced apoptosis. Caspase 8 catalyzes an essential intermediate step in the ubiquitination and proteasome-mediated degradation of IRF3(PMID:21816816). It may control diabetic embryopathy-associated apoptosis via Caspase 8 is expressed as nine isoforms by alternative splicing with the molecular mass from 26 kDa to 62 kDa. This antibodycan recognize pro-and cleaved-caspase 8.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Caspase 8, also named as MCH5, MACH, FLICE, and CAP4, belongs to the peptidase C14A family. It may participate in the GZMB apoptotic pathways and functions as an upstream regulator in a-bisabolol-induced apoptosis. Caspase 8 catalyzes an essential intermediate step in the ubiquitination and proteasome-mediated degradation of IRF3(PMID:21816816 ). It may control diabetic embryopathy-associated apoptosis via Caspase 8 is expressed as nine isoforms by alternative splicing with the molecular mass from 26 kDa to 62 kDa. 66093-1-AP can recognize pro- and cleaved-caspase 8.
Host	Rabbit
Immunogen	caspase 8, apoptosis-related cysteine peptidase
Isotype	IgG
Molecular Weight	50-55 kDa, 25-32 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	Apoptotic cysteine protease, Apoptotic protease Mch 5, Casp 8, CASP8, Caspase 8, Caspase 8/p18, Caspase8, FADD like ICE, FLICE, ICE like apoptotic protease 5, MACH, MCH5

Uniprot	Q14790
Gene Id	841
Research Area	Metabolism
Weight	30-60kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC, IP, IF

Description

ELISA ; WB ; IHC ; IP ; IF

Dilution

WB	1:200-1:2000
IP	1:200-1:2000
IHC	1:50-1:100
IF	1:10-1:100

Tested Application

WB: 1:200-1:2000; IP: 1:200-1:2000; IHC: 1:50-1:100; IF: 1:10-1:100

Manual	FNab01293.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10801288	FNab01293	100ug	$240		Add to Cart

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