Plays a role in signaling mediated by TRAF2, TRAF3 and TRAF6 and protects cells against apoptosis. Activates NF-kappa-B via BCL10 and IKK. Stimulates the phosphorylation of BCL10.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Plays a role in signaling mediated by TRAF2, TRAF3 and TRAF6 and protects cells against apoptosis. Activates NF-kappa-B via BCL10 and IKK. Stimulates the phosphorylation of BCL10.
Host
Rabbit
Immunogen
caspase recruitment domain family, member 14
Isotype
IgG
Molecular Weight
113-120 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
CARMA2
Uniprot
Q9BXL6
Gene Id
79092
Research Area
Immunology, Signal Transduction
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)