Calbindin 2 (calretinin), is an intracellular calcium-binding protein belonging to the troponin C superfamily. Members of this protein family have six EF-hand domains which bind calcium. This protein plays a role in diverse cellular functions, including message targeting and intracellular calcium buffering. It also functions as a modulator of neuronal excitability, and is a diagnostic marker for some human diseases, including Hirschsprung disease and some cancers. Calretinin is a useful marker for differentiating malignant mesothelioma from carcinomas.
Categories
Primary Antibodies
Clonality
polyclonal
Host
Rabbit
Immunogen
calbindin 2
Isotype
IgG
Molecular Weight
32kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
CAB29, CAL2, CR, CALB2
Uniprot
P22676
Gene Id
794
Research Area
Signal Transduction, Neuroscience
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)