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Home / Primary Antibodies / Polyclonal Antibodies

CAD antibody

SKU : BHA10801178

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Mfr.No.	FNab01183
Background	The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. Alternative splicing results in multiple transcript variants encoding different isoforms.
Categories	Primary Antibodies
Clonality	polyclonal
Description	This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase).
Host	Rabbit
Immunogen	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
Isotype	IgG
Molecular Weight	243 kDa
Reactivity	Human
Regulatory	RUO

Uniprot	P27708
Gene Id	790
Research Area	Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB
Description	ELISA ; WB
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:100

Manual	FNab01183.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10801178	FNab01183	100ug	$240		Add to Cart

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