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Home / Primary Antibodies / Polyclonal Antibodies

CACNA1B antibody

SKU : BHA10801166

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Mfr.No.	FNab01171
Alternative Names	CACH5 ; CACNL1A5
Background	Voltage-sensitive calcium channels(VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. N-type calcium channels belong to the 'high-voltage activated'(HVA) group and are blocked by omega-conotoxin-GVIA(omega-CTx-GVIA) and by omega-agatoxin-IIIA(omega-Aga-IIIA). They are however insensitive to dihydropyridines(DHP), and omega-agatoxin-IVA(omega-Aga-IVA). Calcium channels containing alpha-1B subunit may play a role in directed migration of immature neurons.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. N-type calcium channels belong to the 'high-voltage activated' (HVA) group and are blocked by omega-conotoxin-GVIA (omega-CTx-GVIA) and by omega-agatoxin- IIIA (omega-Aga-IIIA). They are however insensitive to dihydropyridines (DHP), and omega-agatoxin-IVA (omega-Aga-IVA). Calcium channels containing alpha-1B subunit may play a role in directed migration of immature neurons.
Host	Rabbit
Immunogen	calcium channel, voltage-dependent, N type, alpha 1B subunit
Isotype	IgG
Molecular Weight	262 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	BIII, Brain calcium channel III, CACH5, CACNA1B, CACNL1A5, CACNN, Cav2.2

Uniprot	Q00975
Gene Id	774
Research Area	Neuroscience

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC
Description	ELISA ; WB ; IHC
Tested Application	WB: 1:200-1:1000; IHC: 1:50-1:500

Manual	FNab01171.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10801166	FNab01171	100ug	$260		Add to Cart

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