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Home / Primary Antibodies / Polyclonal Antibodies

c-MYC antibody

SKU : BHA10801785

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Mfr.No.	FNab01791
Alternative Names	BHLHe39 ; cMyc ; c-Myc ; MRTL ; MYC ; Mycprotooncogeneprotein ; ProtooncogenecMyc ; Transcriptionfactorp64
Background	MYC contains one basic helix-loop-helix(bHLH) domain. This protein is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. It seems to activate the transcription of growth-related genes. It binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC(GA)TG-3'. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. This antibody is a rabbit polyclonal antibody raised against recombinant protein of human MYC.The 50kDa band recognized by antibody is the native form of MYC, while the other bands, between 60-70kDa, are the phosphorylated form of MYC (PMID: 12189186)
Categories	Primary Antibodies
Clonality	polyclonal
Description	MYC contains one basic helix-loop-helix (bHLH) domain. This protein is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. It seems to activate the transcription of growth-related genes. It binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. This antibody is a rabbit polyclonal antibody raised against recombinant protein of human MYC.The 50kDa band recognized by antibody is the native form of MYC, while the other bands, between 60-70kDa, are the phosphorylated form of MYC [PMID: 12189186]
Host	Rabbit
Immunogen	v-myc myelocytomatosis viral oncogene homolog(avian)
Isotype	IgG
Molecular Weight	62-65 kDa, 50 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Synonyms	BHLHe39, c Myc, c-Myc, MRTL, MYC, Myc proto oncogene protein, Proto oncogene c Myc, Transcription factor p64

Uniprot	P01106
Research Area	Epigenetics, Cell Division and Proliferation, Metabolism, Immunology, Cancer, Stem Cells, Neuroscience
Weight	50kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IP, IHC

Description

ELISA ; WB ; IP ; IHC

Dilution

WB	1:500-1:5000
IP	1:200-1:2000
IHC	1:50-1:200

Tested Application

WB: 1:500-1:5000; IP: 1:200-1:2000; IHC: 1:50-1:200

Manual	FNab01791.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10801785	FNab01791	100ug	$280		Add to Cart

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