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Home / Primary Antibodies / Polyclonal Antibodies

c-Met antibody

SKU : BHA10801781

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Mfr.No.	FNab01786
Background	c-Met(also named as MET or HGFR) is a receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. c-Met regulates many physiological processes including proliferation, scattering, morphogenesis and survival. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Overexpression and/or mutation of c-Met has been reported in various human malignancies, including lung cancer, breast cancer, head and neck cancer, gastric cancer, colorectal cancer, bladder cancer, uterine cervix carcinoma, and esophageal carcinoma, c-Met could serve as an important therapeutic target(PMID: 26036285). This antibody recognizes the N-term of c-Met.
Categories	Primary Antibodies
Clonality	polyclonal
Host	Rabbit
Immunogen	met proto-oncogene(hepatocyte growth factor receptor)
Isotype	IgG
Molecular Weight	150 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	AUTS9, c-Met, HGF receptor, HGF/SF receptor, HGFR, MET, Proto oncogene c Met, RCCP2, Scatter factor receptor, SF receptor, Tyrosine protein kinase Met

Uniprot	P08581
Gene Id	4233
Research Area	Epigenetics, Cell Division and Proliferation, Metabolism, Immunology, Cancer, Stem Cells, Neuroscience

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC
Description	ELISA ; WB ; IHC
Tested Application	WB: 1:500-1:1000; IHC: 1:50-1:200

Manual	FNab01786.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10801781	FNab01786	100ug	$240		Add to Cart

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