BTN1A1, also named as Butyrophilin subfamily 1 member A1, is a 526 amino acid protein, which contains 1 B30.2/SPRY domain and belongs to the immunoglobulin superfamily. BTN/MOG family. BTN1A1 localizes in the integral component of plasma membrane. BTN1A1 may function in the secretion of milk-fat droplets and may act as a specific membrane-associated receptor for the association of cytoplasmic droplets with the apical plasma membrane. BTN1A1 Inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion. The calculated molecular weight of BTN1A1 is a 59 kDa, but the modified BTN1A1 protein is about 65-75 kDa.
Clonality
polyclonal
Host
Rabbit
Immunogen
butyrophilin, subfamily 1, member A1
Immunogen Region
butyrophilin, subfamily 1, member A1
Isotype
IgG
Molecular Weight
73 kDa
Reactivity
Human
Recommended Dilution
WB: 1:500-1:5000
Synonyms
BT, BTN, BTN1A1
Uniprot
Q13410
Research Area
Developmental biology, Immunology
Form
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Tested Application
WB: 1:500-1:5000
Product Manual
<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab09786.pdf" target="_blank">Data Sheet</ a>