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Home / Primary Antibodies / Polyclonal Antibodies

BRAF antibody

SKU : BHA10800936

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Mfr.No.	FNab00941
Alternative Names	BRAF1 ; RAFB1
Background	This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Protein kinase involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May play a role in the postsynaptic responses of hippocampal neuron. Phosphorylates MAP2K1, and thereby contributes to the MAP kinase signal transduction pathway.
Host	Rabbit
Immunogen	v-raf murine sarcoma viral oncogene homolog B1
Isotype	IgG
Molecular Weight	98 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	BRAF1, RAFB1

Uniprot	P15056
Gene Id	673
Research Area	Cell Division and Proliferation, Cancer, Cardiovascular, Signal Transduction

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC
Description	ELISA ; WB ; IHC
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab00941.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10800936	FNab00941	100ug	$280		Add to Cart

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