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Home / Primary Antibodies / Monoclonal Antibodies

BORIS antibody

SKU : BHA10800927

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Mfr.No.	FNab00932
Background	CTCFL, also named BORIS(for brother of the regulator of imprinted sites) is a paralogue of the 11 zinc-finger transcription factor, CTCF. It is predominantly expressed in spermatocytes in the testis, also can be found in tumors and cancer cell lines. It mainly participates in insulator function, nuclear architecture and transcriptional control, which probably acts by recruiting epigenetic chromatin modifiers. It has a key role in gene imprinting in male germline, by participating in the establishment of differential methylation at the IGF2/H19 imprinted control region(ICR). Directly binds the unmethylated H19 ICR and recruits the PRMT7 methyltransferase, leading to methylate histone H4 'Arg-3' to form H4R3sme2.
Categories	Primary Antibodies
Clonality	monoclonal
Host	Mouse
Immunogen	CCCTC-binding factor(zinc finger protein)-like
Isotype	IgG1
Molecular Weight	75 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Synonyms	BORIS, Cancer/testis antigen 27, CCCTC binding factor, CT27, CTCF like protein, CTCF paralog, CTCF T, CTCFL, dJ579F20.2, Zinc finger protein CTCF T

Uniprot	Q8NI51
Clone No	2B10
Research Area	Metabolism

Form	liquid
Format	liquid
Purification	Protein A+G purification
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IF
Description	ELISA ; WB ; IF
Tested Application	WB: 1:500-1:2000; IF: 1:10-1:100

Manual	FNab00932.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10800927	FNab00932	100ug	$280		Add to Cart

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