The major proteolytic product p15 BID allows the release of cytochrome c(By similarity). Isoform 1, isoform 2 and isoform 4 induce ICE-like proteases and apoptosis. Isoform 3 does not induce apoptosis. Counters the protective effect of Bcl-2.
Categories
Primary Antibodies
Clonality
monoclonal
Description
The major proteolytic product p15 BID allows the release of cytochrome c (By similarity). Isoform 1, isoform 2 and isoform 4 induce ICE-like proteases and apoptosis. Isoform 3 does not induce apoptosis. Counters the protective effect of Bcl-2.
Host
Mouse
Immunogen
BH3 interacting domain death agonist
Isotype
IgG2a
Molecular Weight
22 kDa
Reactivity
Human
Regulatory
RUO
Synonyms
BID, FP497, p11 BID, p22 BID
Uniprot
P55957
Gene Id
637
Clone No
6E8
Research Area
Metabolism, Cell Division and Proliferation, Cancer, Signal Transduction
Form
liquid
Format
liquid
Purification
Protein A+G purification
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)