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Home / Primary Antibodies / Polyclonal Antibodies

BEX2 antibody

SKU : BHA10800879

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Mfr.No.	FNab00884
Background	Regulator of mitochondrial apoptosis and G1 cell cycle in breast cancer. Protects the breast cancer cells against mitochondrial apoptosis and this effect is mediated through the modulation of BCL2 protein family, which involves the positive regulation of anti-apoptotic member BCL2 and the negative regulation of pro-apoptotic members BAD, BAK1 and PUMA. Required for the normal cell cycle progression during G1 in breast cancer cells through the regulation of CCND1 and CDKN1A. Regulates the level of PP2A regulatory subunit B and PP2A phosphatase activity. The homology between human BEX1 and BEX2 is 94%. This antibody detects both BEX1 and BEX2.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Regulator of mitochondrial apoptosis and G1 cell cycle in breast cancer. Protects the breast cancer cells against mitochondrial apoptosis and this effect is mediated through the modulation of BCL2 protein family, which involves the positive regulation of anti-apoptotic member BCL2 and the negative regulation of pro-apoptotic members BAD, BAK1 and PUMA. Required for the normal cell cycle progression during G1 in breast cancer cells through the regulation of CCND1 and CDKN1A. Regulates the level of PP2A regulatory subunit B and PP2A phosphatase activity.
Host	Rabbit
Immunogen	brain expressed X-linked 2
Isotype	IgG
Molecular Weight	10-15 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	BEX1, BEX1/2, BEX2, brain expressed X linked 2, hBex2, Protein BEX2

Uniprot	Q9BXY8
Gene Id	84707
Research Area	Signal Transduction, Cancer, Neuroscience

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC
Description	ELISA ; WB ; IHC
Tested Application	WB: 1:500-1:1000; IHC: 1:20-1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10800879	FNab00884	100ug	$240		Add to Cart

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