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Home / Primary Antibodies / Polyclonal Antibodies

Beclin 1 antibody

SKU : BHA10800855

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Mfr.No.	FNab00860
Alternative Names	ATG6 ; Beclin1 ; beclin1 ; autophagyrelated ; beclin1 ; BECN1 ; GT197 ; ProteinGT197 ; VPS30
Background	Beclin-1(BECN1), also known as ATG6 or VPS30, has a central role in autophagy, a process of programmed cell survival, which is increased during periods of cell stress and extinguished during the cell cycle. Beclin-1, may play a role in antiviral host defense. It protects against infection by a neurovirulent strain of Sindbis virus. Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration. A progressively reduced Beclin-1 expression is reported to correlate with the primary tumor growth of squamous cell carcinoma and adenocarcinoma of the lung. Caspase-mediated cleavage of Beclin 1 promotes crosstalk between apoptosis and autophagy.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Beclin-1 (BECN1), also known as ATG6 or VPS30, has a central role in autophagy, a process of programmed cell survival, which is increased during periods of cell stress and extinguished during the cell cycle. Beclin-1, may play a role in antiviral host defense. It protects against infection by a neurovirulent strain of Sindbis virus. Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration. A progressively reduced Beclin-1 expression is reported to correlate with the primary tumor growth of squamous cell carcinoma and adenocarcinoma of the lung. Caspase-mediated cleavage of Beclin 1 promotes crosstalk between apoptosis and autophagy.
Host	Rabbit
Immunogen	beclin 1, autophagy related
Isotype	IgG
Molecular Weight	60 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	ATG6, Beclin 1, beclin 1, autophagy related, beclin1, BECN1, GT197, Protein GT197, VPS30

Uniprot	Q14457
Gene Id	8678
Research Area	Cancer, Immunology, Metabolism
Weight	60kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, IHC, IP, WB, IF

Description

ELISA ; IHC ; IP ; WB ; IF

Dilution

WB	1:500-1:5000
IP	1:200-1:2000
IHC	1:20-1:200
IF	1:20-1:200

Tested Application

WB: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:20-1:200

Manual	FNab00860.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10800855	FNab00860	100ug	$260		Add to Cart

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