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Home / Primary Antibodies / Polyclonal Antibodies

BCS1L antibody

SKU : BHA10800851

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Mfr.No.	FNab00856
Alternative Names	BCS1
Background	This gene encodes a homolog of the S. cerevisiae bcs1 protein which is involved in the assembly of complex III of the mitochondrial respiratory chain. The encoded protein does not contain a mitochondrial targeting sequence but experimental studies confirm that it is imported into mitochondria. Mutations in this gene are associated with mitochondrial complex III deficiency and the GRACILE syndrome. Several alternatively spliced transcripts encoding two different isoforms have been described.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Chaperone necessary for the assembly of mitochondrial respiratory chain complex III. Plays an important role in the maintenance of mitochondrial tubular networks, respiratory chain assembly and formation of the LETM1 complex.
Host	Rabbit
Immunogen	BCS1-like (yeast)
Isotype	IgG
Molecular Weight	48 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	BCS1

Uniprot	Q9Y276
Gene Id	617
Research Area	Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC
Description	ELISA ; WB ; IHC
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab00856.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10800851	FNab00856	100ug	$260		Add to Cart

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