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Home / Primary Antibodies / Polyclonal Antibodies

BCOR antibody

SKU : BHA10800848

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Mfr.No.	FNab00853
Alternative Names	KIAA1575
Background	Transcriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence-specific DNA-binding proteins such as BCL6 and MLLT3. This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor. Involved in the repression of TFAP2A; impairs binding of BCL6 and KDM2B to TFAP2A promoter regions. Via repression of TFAP2A acts as a negative regulator of osteo-dentiogenic capacity in adult stem cells; the function implies inhibition of methylation on histone H3 'Lys-4'(H3K4me3) and 'Lys-36'(H3K36me2).
Categories	Primary Antibodies
Clonality	polyclonal
Description	Transcriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence- specific DNA-binding proteins such as BCL6 and MLLT3. This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor. Involved in the repression of TFAP2A; impairs binding of BCL6 and KDM2B to TFAP2A promoter regions. Via repression of TFAP2A acts as a negative regulator of osteo-dentiogenic capacity in adult stem cells; the function implies inhibition of methylation on histone H3 'Lys-4' (H3K4me3) and 'Lys-36' (H3K36me2).
Host	Rabbit
Immunogen	BCL6 co-repressor
Isotype	IgG
Molecular Weight	186 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	KIAA1575

Uniprot	Q6W2J9
Gene Id	54880
Research Area	Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB
Description	ELISA ; WB
Tested Application	WB: 1:500 - 1:2000

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SKU	Supplier No.	Size	Your price	Quantity
BHA10800848	FNab00853	100ug	$260		Add to Cart

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