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Home / Primary Antibodies / Monoclonal Antibodies

BCL2 antibody

SKU : BHA10800835

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Mfr.No.	FNab00840
Background	Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor(APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release(PubMed:17418785).
Categories	Primary Antibodies
Clonality	monoclonal
Description	Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (PubMed:17418785).
Host	Mouse
Immunogen	B-cell CLL/lymphoma 2
Isotype	IgG2a
Molecular Weight	26 kDa
Reactivity	Human
Regulatory	RUO
Synonyms	Apoptosis regulator Bcl 2, B cell CLL/lymphoma 2, BCL2, Oncogene B cell leukemia 2

Uniprot	P10415
Gene Id	596
Clone No	8A10
Research Area	Cancer, Immunology, Cardiovascular, Neuroscience

Form	liquid
Format	liquid
Purification	Protein A+G purification
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, FC, IP, IHC
Description	ELISA ; WB ; FC ; IP ; IHC
Tested Application	WB: 1:1000-1:10000; IP: 1:500-1:5000; IHC: 1:100-1:2000

Manual	FNab00840.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10800835	FNab00840	100ug	$260		Add to Cart

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