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Home / Primary Antibodies

Bcl-x Polyclonal Antibody

SKU : BHA13715195

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Abbkine Scientific Co., Ltd.

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Mfr.No.	ABP0063
Background	The protein (BCL2 like 1) encoded by BCL2L1belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Alternative splicing results in multiple transcript variants encoding two different isoforms. The longer isoform acts as an apoptotic inhibitor and the shorter isoform acts as an apoptotic activator
Clonality	Polyclonal
Formulation	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Host	Rabbit
Immunogen	Synthesized peptide derived from human Bcl-x around the non-phosphorylation site of S62
Isotype	Rabbit IgG
Reactivity	Human, Mouse, Rat

Gene Id	598

Concentration	1 mg/ml
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Storage Buffer	PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide

Applications	Protein General Reagents

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SKU	Supplier No.	Size	Your price	Quantity
BHA13715195	ABP0063	100ul	$229		Add to Cart

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