Plays a role in angiogenesis. Participates in the regulation of cell polarity and directional endothelial cell migration by mediating both the activation and recruitment of CDC42 and the reorganization of the actin cytoskeleton at the cell leading edge. Promotes filipodia formation (By similarity). Functions synergistically with PELP1 as a transcriptional coactivator of estrogen receptor-responsive genes. Stimulates histone acetyltransferase activity. Binds to chromatin.
Host
Rabbit
Immunogen
breast carcinoma amplified sequence 3
Isotype
IgG
Molecular Weight
115 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
GAOB1;MAAB
Uniprot
Q9H6U6
Gene Id
54828
Research Area
Stem Cells
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)