Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR).
Host
Rabbit
Immunogen
breast carcinoma amplified sequence 2
Isotype
IgG
Molecular Weight
25 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
DAM1;SPF27;Snt309
Uniprot
O75934
Gene Id
10286
Research Area
Metabolism, Neuroscience
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)