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Home / Primary Antibodies / Polyclonal Antibodies

BAX antibody

SKU : BHA10810365

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Mfr.No.	FNab10410
Background	The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene.
Clonality	polyclonal
Host	Rabbit
Immunogen	BCL2-associated X protein
Immunogen Region	BCL2-associated X protein
Isotype	IgG
Molecular Weight	21 kDa
Reactivity	Human
Recommended Dilution	WB: 1:500-1:2000
Synonyms	BCL2L4, Apoptosis regulator BAX, BAX

Uniprot	Q07812
Gene Id	581
Research Area	Developmental biology, Cancer, Neuroscience

Form	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Application	WB: 1:500-1:2000

Product Manual	<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10410.pdf" target="_blank">Data Sheet</ a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA10810365	FNab10410	100ug	$240		Add to Cart

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