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Home / Primary Antibodies / Polyclonal Antibodies

BATF2 antibody

SKU : BHA10800803

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Mfr.No.	FNab00808
Background	AP-1 family transcription factor that controls the differentiation of lineage-specific cells in the immune system. Following infection, participates in the differentiation of CD8(+) thymic conventional dendritic cells in the immune system. Acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5'-TGA(CG)TCA-3' and regulates expression of target genes(By similarity). Selectively suppresses CYR61/CCN1 transcription and hence blocks the downstream cell proliferation signals produced by CYR61 and inhibits CYR61-induced anchorage-independent growth and invasion in several cancer types, such as breast cancer, malignant glioma and metastatic melanoma. Possibly acts by interfering with AP-1 binding to CYR61 promoter.
Categories	Primary Antibodies
Clonality	polyclonal
Description	AP-1 family transcription factor that controls the differentiation of lineage-specific cells in the immune system. Following infection, participates in the differentiation of CD8(+) thymic conventional dendritic cells in the immune system. Acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5'-TGA[CG]TCA-3' and regulates expression of target genes (By similarity). Selectively suppresses CYR61/CCN1 transcription and hence blocks the downstream cell proliferation signals produced by CYR61 and inhibits CYR61-induced anchorage-independent growth and invasion in several cancer types, such as breast cancer, malignant glioma and metastatic melanoma. Possibly acts by interfering with AP-1 binding to CYR61 promoter.
Host	Rabbit
Immunogen	basic leucine zipper transcription factor, ATF-like 2
Isotype	IgG
Molecular Weight	29 kDa
Reactivity	Human
Regulatory	RUO
Synonyms	B ATF 2, BATF2, basic leucine zipper transcription factor,ATF-like 2

Uniprot	Q8N1L9
Gene Id	116071
Research Area	Epigenetics, Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, IP
Description	ELISA ; IP
Tested Application	WB: 1:200-1:1000; IP: 1:200-1:1000

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SKU	Supplier No.	Size	Your price	Quantity
BHA10800803	FNab00808	100ug	$240		Add to Cart

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