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Home / Primary Antibodies / Polyclonal Antibodies

BAG1 antibody

SKU : BHA10800781

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Mfr.No.	FNab00786
Alternative Names	HAP
Background	The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti- apoptotic effects of BCL2 and represents a link between growth factor receptors and anti- apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Inhibits the pro-apoptotic function of PPP1R15A, and has anti-apoptotic activity. Markedly increases the anti-cell death function of BCL2 induced by various stimuli.
Host	Rabbit
Immunogen	BCL2-associated athanogene
Isotype	IgG
Molecular Weight	43 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Synonyms	HAP

Uniprot	Q99933
Gene Id	573
Research Area	Cardiovascular, Signal Transduction

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC, IF, IP
Description	ELISA ; WB ; IHC ; IF ; IP
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:20 - 1:100

Manual	FNab00786.pdf

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10800781	FNab00786	100ug	$240		Add to Cart

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