Inhibitor of the Wnt signaling pathway. Down-regulates beta-catenin. Probably facilitate the phosphorylation of beta-catenin and APC by GSK3B(By similarity).
Categories
Primary Antibodies
Clonality
polyclonal
Description
Inhibitor of the Wnt signaling pathway. Down-regulates beta-catenin. Probably facilitate the phosphorylation of beta- catenin and APC by GSK3B (By similarity).
Host
Rabbit
Immunogen
axin 2
Isotype
IgG
Molecular Weight
93-100 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
AXIL, axin 2, Axin like protein, AXIN2, Axis inhibition protein 2, Conductin
Uniprot
Q9Y2T1
Gene Id
8313
Research Area
Cell Division and Proliferation, Developmental biology, Cancer, Signal Transduction
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)