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Home / Primary Antibodies / Polyclonal Antibodies

ATPIF1 antibody

SKU : BHA10800730

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Mfr.No.	FNab00735
Alternative Names	ATPI
Background	This gene encodes a mitochondrial ATPase inhibitor. Alternative splicing occurs at this locus and three transcript variants encoding distinct isoforms have been identified.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Endogenous F(1)F(o)-ATPase inhibitor limiting ATP depletion when the mitochondrial membrane potential falls below a threshold and the F(1)F(o)-ATP synthase starts hydrolyzing ATP to pump protons out of the mitochondrial matrix. Required to avoid the consumption of cellular ATP when the F(1)F(o)-ATP synthase enzyme acts as an ATP hydrolase. Indirectly acts as a regulator of heme synthesis in erythroid tissues: regulates heme synthesis by modulating the mitochondrial pH and redox potential, allowing FECH to efficiently catalyze the incorporation of iron into protoporphyrin IX to produce heme.
Host	Rabbit
Immunogen	ATPase inhibitory factor 1
Isotype	IgG
Molecular Weight	12 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Synonyms	ATPI

Uniprot	Q9UII2
Gene Id	93974
Research Area	Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB
Description	ELISA ; WB
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:100

Manual	FNab00735.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10800730	FNab00735	100ug	$260		Add to Cart

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