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Home / Primary Antibodies / Polyclonal Antibodies

ATP1B1 antibody

SKU : BHA10800691

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Mfr.No.	FNab00696
Alternative Names	ATP1B
Background	The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 1 subunit. Alternatively spliced transcript variants encoding different isoforms have been described, but their biological validity is not known.
Categories	Primary Antibodies
Clonality	polyclonal
Description	This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. Involved in cell adhesion and establishing epithelial cell polarity.
Host	Rabbit
Immunogen	ATPase, Na+/K+ transporting, beta 1 polypeptide
Isotype	IgG
Molecular Weight	36 kDa, 50 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	ATP1B

Uniprot	P05026
Gene Id	481
Research Area	Metabolism, Neuroscience

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC, FC, IF, IP
Description	ELISA ; WB ; IHC ; FC ; IF ; IP
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab00696.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10800691	FNab00696	100ug	$240		Add to Cart

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