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Home / Primary Antibodies / Polyclonal Antibodies

ATG4B antibody

SKU : BHA10800669

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Mfr.No.	FNab00674
Alternative Names	APG4B ; AUTL1 ; KIAA0943
Background	Cysteine protease required for the cytoplasm to vacuole transport(Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine(PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C- terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.
Host	Rabbit
Immunogen	ATG4 autophagy related 4 homolog B
Isotype	IgG
Molecular Weight	44 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	APG4B, AUTL1, KIAA0943

Uniprot	Q9Y4P1
Gene Id	23192
Research Area	Cardiovascular, Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC, IP
Description	ELISA ; WB ; IHC ; IP
Tested Application	WB: 1:500-1:2000; IP: 1:500-1:2000 ; IHC: 1:20-1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10800669	FNab00674	100ug	$240		Add to Cart

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