ATPase that plays a critical role in regulating the surface expression of AMPA receptors(AMPAR), thereby regulating synaptic plasticity and learning and memory. Required for NMDA-stimulated AMPAR internalization and inhibition of GRIA1 and GRIA2 recycling back to the plasma membrane; these activities are ATPase-dependent(By similarity).
Categories
Primary Antibodies
Clonality
polyclonal
Description
ATPase that plays a critical role in regulating the surface expression of AMPA receptors (AMPAR), thereby regulating synaptic plasticity and learning and memory. Required for NMDA- stimulated AMPAR internalization and inhibition of GRIA1 and GRIA2 recycling back to the plasma membrane; these activities are ATPase-dependent (By similarity).
Host
Rabbit
Immunogen
ATPase family, AAA domain containing 1
Isotype
IgG
Molecular Weight
32 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
AFDC1, ATAD1, FNP001
Uniprot
Q8NBU5
Gene Id
84896
Research Area
Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)