Component of the Set1/Ash2 histone methyltransferase(HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis.
Host
Rabbit
Immunogen
ash2(absent, small, or homeotic)-like(Drosophila)
Isotype
IgG
Molecular Weight
80 kDa
Reactivity
Human, Mouse, Rat, Monkey
Regulatory
RUO
Synonyms
ASH2L1
Uniprot
Q9UBL3
Gene Id
9070
Research Area
Epigenetics, Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)