Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1(CAF-1) to promote replication-dependent chromatin assembly. Does not participate in replication-independent nucleosome deposition which is mediated by ASF1A and HIRA. Required for spermatogenesis.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly. Does not participate in replication-independent nucleosome deposition which is mediated by ASF1A and HIRA. Required for spermatogenesis.
Host
Rabbit
Immunogen
ASF1 anti-silencing function 1 homolog B
Isotype
IgG
Molecular Weight
19 kDa
Reactivity
Human
Regulatory
RUO
Synonyms
ASF1B, CCG1 interacting factor A II, CIA II, hAsf1, hAsf1b, hCIA II, Histone chaperone ASF1B
Uniprot
Q9NVP2
Gene Id
55723
Research Area
Epigenetics, Developmental biology, Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)