May act as a GTPase-activating protein for RAB2A, RAB8A, RAB10 and RAB14. Isoform 2 promotes insulin-induced glucose transporter SLC2A4/GLUT4 translocation at the plasma membrane, thus increasing glucose uptake.
Clonality
polyclonal
Host
Rabbit
Immunogen
AS160
Immunogen Region
AS160
Isotype
IgG
Molecular Weight
147 kDa
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:500 - 1:2000
Synonyms
TBC1D4, AS160, NIDDM5, TBC1 domain family member 4, TBC (Tre-2, BUB2, CDC16) domain-containing protein, akt substrate of 160 kDa
Uniprot
O60343
Research Area
Signal Transduction
Form
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Application
WB: 1:500 - 1:2000
Product Manual
<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab09889.pdf" target="_blank">Data Sheet</ a>