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Home / Primary Antibodies / Polyclonal Antibodies

ARRDC3 antibody

SKU : BHA10800603

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Mfr.No.	FNab00608
Alternative Names	KIAA1376
Background	Adapter protein that plays a role in regulating cell-surface expression of adrenergic receptors and probably also other G protein-coupled receptors(PubMed:20559325, PubMed:21982743, PubMed:23208550). Plays a role in NEDD4-mediated ubiquitination and endocytosis af activated ADRB2 and subsequent ADRB2 degradation(PubMed:20559325, PubMed:23208550). May recruit NEDD4 to ADRB2(PubMed:20559325). Alternatively, may function as adapter protein that does not play a major role in recruiting NEDD4 to ADRB2, but rather plays a role in a targeting ADRB2 to endosomes(PubMed:23208550).
Categories	Primary Antibodies
Clonality	polyclonal
Description	Adapter protein that plays a role in regulating cell- surface expression of adrenergic receptors and probably also other G protein-coupled receptors (PubMed:20559325, PubMed:21982743, PubMed:23208550). Plays a role in NEDD4-mediated ubiquitination and endocytosis af activated ADRB2 and subsequent ADRB2 degradation (PubMed:20559325, PubMed:23208550). May recruit NEDD4 to ADRB2 (PubMed:20559325). Alternatively, may function as adapter protein that does not play a major role in recruiting NEDD4 to ADRB2, but rather plays a role in a targeting ADRB2 to endosomes (PubMed:23208550).
Host	Rabbit
Immunogen	arrestin domain containing 3
Isotype	IgG
Molecular Weight	46 kDa
Reactivity	Human
Regulatory	RUO
Synonyms	ARRDC3, arrestin domain containing 3, KIAA1376, TLIMP

Uniprot	Q96B67
Gene Id	57561
Research Area	Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IF
Description	ELISA ; WB ; IF
Tested Application	WB: 1:500-1:1000; IF: 1:10-1:100

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SKU	Supplier No.	Size	Your price	Quantity
BHA10800603	FNab00608	100ug	$240		Add to Cart

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