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Home / Primary Antibodies / Polyclonal Antibodies

ARL3 antibody

SKU : BHA10800571

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Mfr.No.	FNab00576
Alternative Names	ARFL3
Background	Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors(GEF) and GTPase-activating proteins(GAP). Required for normal cytokinesis and cilia signaling. Requires assistance from GTPase-activating proteins(GAPs) like RP2 and PDE6D, in order to cycle between inactive GDP-bound and active GTP-bound forms. Required for targeting proteins such as NPHP3 to the ciliary membrane by releasing myristoylated NPHP3 from UNC119B cargo adapter into the cilium. Does not act as an allosteric activator of the cholera toxin catalytic subunit.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). Required for normal cytokinesis and cilia signaling. Requires assistance from GTPase- activating proteins (GAPs) like RP2 and PDE6D, in order to cycle between inactive GDP-bound and active GTP-bound forms. Required for targeting proteins such as NPHP3 to the ciliary membrane by releasing myristoylated NPHP3 from UNC119B cargo adapter into the cilium. Does not act as an allosteric activator of the cholera toxin catalytic subunit.
Host	Rabbit
Immunogen	ADP-ribosylation factor-like 3
Isotype	IgG
Molecular Weight	20 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	ARFL3

Uniprot	P36405
Gene Id	403
Research Area	Signal Transduction

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC, IF
Description	ELISA ; WB ; IHC ; IF
Tested Application	WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10800571	FNab00576	100ug	$260		Add to Cart

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