Cilium-specific protein required to control the microtubule-based, ciliary axoneme structure. May act by maintaining the association between IFT subcomplexes A and B. Binds GTP but is not able to hydrolyze it; the GTPase activity remains unclear. Required to pattern the neural tube. Involved in cerebral cortex development: required for the initial formation of a polarized radial glial scaffold, the first step in the construction of the cerebral cortex, by regulating ciliary signaling. Regulates the migration and placement of postmitotic interneurons in the developing cerebral cortex. May regulate endocytic recycling traffic; however, additional evidences are required to confirm these data.
Clonality
polyclonal
Host
Rabbit
Immunogen
ADP-ribosylation factor-like 13B
Immunogen Region
ADP-ribosylation factor-like 13B
Isotype
IgG
Molecular Weight
40-48 kDa, 60 kDa
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:500-1:2000
Synonyms
ARL13B, ARL2 like protein 1, ARL2L1, JBTS8
Uniprot
Q3SXY8
Gene Id
200894
Research Area
Signal Transduction
Form
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Tested Application
WB: 1:500-1:2000
Product Manual
<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10390.pdf" target="_blank">Data Sheet</ a>