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Home / Primary Antibodies / Polyclonal Antibodies

ARHGEF1 antibody

SKU : BHA10800553

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Mfr.No.	FNab00558
Background	Seems to play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12(GNA12) and alpha-13(GNA13) subunits. Acts as GTPase-activating protein(GAP) for GNA12 and GNA13, and as guanine nucleotide exchange factor(GEF) for RhoA GTPase. Activated G alpha 13/GNA13 stimulates the RhoGEF activity through interaction with the RGS-like domain. This GEF activity is inhibited by binding to activated GNA12. Mediates angiotensin-2-induced RhoA activation.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Seems to play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13) subunits. Acts as GTPase-activating protein (GAP) for GNA12 and GNA13, and as guanine nucleotide exchange factor (GEF) for RhoA GTPase. Activated G alpha 13/GNA13 stimulates the RhoGEF activity through interaction with the RGS-like domain. This GEF activity is inhibited by binding to activated GNA12. Mediates angiotensin-2- induced RhoA activation.
Host	Rabbit
Immunogen	Rho guanine nucleotide exchange factor(GEF) 1
Isotype	IgG
Molecular Weight	102-110 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Synonyms	ARHGEF1, GEF1, LBCL2, LSC, P115 RHOGEF, p115RhoGEF, SUB1.5

Uniprot	Q92888
Gene Id	9138
Research Area	Signal Transduction, Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, IHC, WB, IP
Description	ELISA ; IHC ; WB ; IP
Tested Application	WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10800553	FNab00558	100ug	$260		Add to Cart

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