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Home / Primary Antibodies / Polyclonal Antibodies

ARHGEF1 antibody

SKU : BHA10810078

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Mfr.No.	FNab10091
Background	Seems to play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12(GNA12) and alpha-13(GNA13) subunits. Acts as GTPase-activating protein(GAP) for GNA12 and GNA13, and as guanine nucleotide exchange factor(GEF) for RhoA GTPase. Activated G alpha 13/GNA13 stimulates the RhoGEF activity through interaction with the RGS-like domain. This GEF activity is inhibited by binding to activated GNA12. Mediates angiotensin-2-induced RhoA activation.
Clonality	polyclonal
Host	Rabbit
Immunogen	Rho guanine nucleotide exchange factor(GEF) 1
Immunogen Region	Rho guanine nucleotide eXchange factor(GEF) 1
Isotype	IgG
Molecular Weight	102-110 kDa
Reactivity	Human, Rat
Recommended Dilution	IHC: 1:20-1:200
Synonyms	ARHGEF1, GEF1, LBCL2, LSC, P115 RHOGEF, p115RhoGEF, SUB1.5, ARHG1

Uniprot	Q92888
Gene Id	9138
Research Area	Signal Transduction, Metabolism

Form	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Tested Application	IHC: 1:20-1:200

Product Manual	<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10091.pdf" target="_blank">Data Sheet</ a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA10810078	FNab10091	100ug	$260		Add to Cart

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