This gene encodes a receptor for anthrax toxin. The protein binds to collagen IV and laminin, suggesting that it may be involved in extracellular matrix adhesion. Mutations in this gene cause juvenile hyaline fibromatosis and infantile systemic hyalinosis. Multiple transcript variants encoding different isoforms have been found for this gene.
Categories
Primary Antibodies
Cellular Localization
Embrane, Secreted
Clonality
polyclonal
Description
Necessary for cellular interactions with laminin and the extracellular matrix.