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Home / Primary Antibodies / Monoclonal Antibodies

Antithrombin III antibody

SKU : BHA10800444

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Mfr.No.	FNab00449
Alternative Names	Antithrombin ; AntithrombinIII ; AT3 ; ATIII ; HEPARINCOFACTORI ; SerpinC1 ; SERPINC1
Background	SERPINC1, also named Antithrombin III or Antithrombin, is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.
Categories	Primary Antibodies
Cellular Localization	Secreted
Clonality	monoclonal
Description	SERPINC1, also named Antithrombin III or Antithrombin, is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.
Host	Mouse
Immunogen	serpin peptidase inhibitor, clade C(antithrombin), member 1
Isotype	IgG1
Molecular Weight	53 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Subcellular Location	Secreted
Synonyms	Antithrombin, Antithrombin III, AT3, ATIII, HEPARIN COFACTOR I, Serpin C1, SERPINC1

Uniprot	P01008
Gene Id	462
Clone No	9A4
Research Area	Cardiovascular, Metabolism
Weight	53kDa

Form	liquid
Format	liquid
Purification	Protein A+G purification
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB

Description

ELISA ; WB

Dilution

WB	1:500-1:5000

Tested Application

WB: 1:500-1:5000

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SKU	Supplier No.	Size	Your price	Quantity
BHA10800444	FNab00449	100ug	$300		Add to Cart

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