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Home / Primary Antibodies / Recombinant Antibodies

Anti-YWHAE Antibody BHA11304064

SKU : BHA11304064

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Mfr.No.	BS6109
Alternative Names	14-3-3 protein epsilon ; 14-3-3E ; YWHAE ; 1433E
Categories	Primary Antibodies
Chromosome Location	17p13.3
Clonality	polyclonal
Description	14-3-3 proteins regulate many cellular processes relevant to cancer biology, notably apoptosis, mitogenic signaling and cell-cycle checkpoints. Seven isoforms comprise this family of signaling intermediates, denoted 14-3-3 β, γ, ε, ζ, η, θ and σ. 14-3-3 proteins form dimers that present two binding sites for ligand proteins, thereby bringing together two proteins that may not otherwise associate. These ligands largely share a 14-3-3 consensus binding motif and exhibit serine/threonine phosphorylation. 14-3-3 proteins function in broad regulation of these ligand proteins, by cytoplasmic sequestration, occupation of interaction domains and import/export sequences, prevention of degradation, activation/repression of enzymatic activity and facilitation of protein modification, and thus loss of expression contributes to a vast array of pathogenic cellular activities.
Host	Rabbit
Immunogen	Recombinant full length Human 14-3-3 ε.
Reactivity	Human, Mouse, Rat
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P62258
Uniprot	P62258
Weight	29 kDa

Description	Product: 1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. Specificity: 14-3-3 ε polyclonal antibody detects endogenous levels of 14-3-3 ε protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:2000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11304064	BS6109	50µl	$234.89		Add to Cart
BHA11304064	BS6109	100µl	$368.22		Add to Cart

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