Anti-undefined Antibody C3e,1931 Unconjugated BHA10208120

Mfr.No.	916-MSM11-P1ABX
Alternative Names	CD3 epsilon ; CD3 TCR complex ; T cell antigen receptor complex epsilon subunit of T3 ; T-cell surface antigen T3/Leu-4 epsilon chain ; T-cell surface glycoprotein CD3 epsilon chain ; T3E ; TCRE ; TiT3 complex
Categories	Primary Antibodies
Cellular Localization	Cytoplasmic, Cell Surface
Chromosome Location	11q23.3
Clonality	monoclonal
Description	Recognizes the ?-chain of CD3, which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms.
Host	Mouse
Immunogen	Recombinant fragment of human CD3e (around aa 23-119) (exact sequence is proprietary)
Isotype	IgG1 Kappa
Positive Control	Jurkat cells. Tonsil or lymph node
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P07766
Gene Id	916
Clone No	C3e, 1931
Symbol	CD3E
Weight	20kDa

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Storage	Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Applications

ELISA, IHC-F

Description

Order Ab without BSA, Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes,Optimal dilution for a specific application should be determined., ELISA ; IHC-F

Dilution