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Home / Primary Antibodies / Recombinant Antibodies

Anti-TRAF6 Antibody BHA11303873

SKU : BHA11303873

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Mfr.No.	BS6076
Alternative Names	E3 ubiquitin-protein ligase TRAF6 ; Interleukin 1 signal transducer ; Interleukin-1 signal transducer ; MGC 3310 ; MGC 3310 ; MGC:3310 ; MGC3310 ; OTTHUMP00000232772 ; OTTHUMP00000232773 ; RING finger protein 85 ; RNF 85 ; RNF85 ; RNF85 ; TNF receptor associated factor 6 ; TNF receptor associated factor 6 ; TNF receptor-associated factor 6 ; TRAF 6 ; Traf6 ; TRAF6
Categories	Primary Antibodies
Chromosome Location	11p12
Clonality	polyclonal
Description	Tumor necrosis factor receptor-associated factor 6 (TRAF6) regulates adaptive immunity, innate immunity and bone metabolism. TRAF6 is a ubiquitin (Ub) ligase that mediates the activation of protein kinases, such as transforming growth factor beta-activated kinase (TAK1) and IκB kinase (IKK), by catalyzing the formation of a unique polyubiquitin chain linked through Lys 63 of Ub. TRAF6 is essential for activating NFκB signaling pathway in response to interleukin-1 and Toll-like receptor ligands. The coiled-coil domain of TRAF6 is essential for its auto-ubiquitination and activating NFκB signaling pathway.
Host	Rabbit
Immunogen	Recombinant full length Human TRAF6.
Reactivity	Human, Mouse, Rat
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	Q9Y4K3
Uniprot	Q9Y4K3
Weight	58 kDa

Description	Product: 1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. Specificity: TRAF6 polyclonal antibody detects endogenous levels of TRAF6 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IF

Description

WB ; IF

Dilution

WB	1:500-1:2000
IF	1:50-1:200

Datasheet

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA11303873	BS6076	50µl	$234.89		Add to Cart
BHA11303873	BS6076	100µl	$368.22		Add to Cart

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