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Home / Primary Antibodies / Recombinant Antibodies

Anti-TRAF2 Antibody BHA11303776

SKU : BHA11303776

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Mfr.No.	BS6065
Alternative Names	TNF receptor-associated factor 2 ; E3 ubiquitin-protein ligase TRAF2 ; Tumor necrosis factor type 2 receptor-associated protein 3 ; TRAF2 ; TRAP3
Categories	Primary Antibodies
Chromosome Location	9q34.3
Clonality	polyclonal
Description	Regulates activation of NF-kappa-B and JNK and plays a central role in the regulation of cell survival and apoptosis. Required for normal antibody isotype switching from IgM to IgG. Has E3 ubiquitin-protein ligase activity and promotes 'Lys-63'-linked ubiquitination of target proteins, such as BIRC3, RIPK1 and TICAM1. Is an essential constituent of several E3 ubiquitin-protein ligase complexes, where it promotes the ubiquitination of target proteins by bringing them into contact with other E3 ubiquitin ligases. Regulates BIRC2 and BIRC3 protein levels by inhibiting their autoubiquitination and subsequent degradation; this does not depend on the TRAF2 RING-type zinc finger domain.
Host	Rabbit
Immunogen	Recombinant full length Human TRAF2.
Reactivity	Human, Mouse, Rat
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	Q12933
Uniprot	Q12933
Weight	56 kDa

Description	Product: 1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. Specificity: TRAF2 polyclonal antibody detects endogenous levels of TRAF2 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IF

Description

WB ; IF

Dilution

WB	1:500-1:2000
IF	1:50-1:200

Datasheet

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA11303776	BS6065	50µl	$234.89		Add to Cart
BHA11303776	BS6065	100µl	$368.22		Add to Cart

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