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Home / Primary Antibodies / Recombinant Antibodies

Anti-TK1 Antibody BHA11307474

SKU : BHA11307474

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Mfr.No.	BS7269
Alternative Names	TK1 ; EC 2.7.1.21 ; TK2
Categories	Primary Antibodies
Chromosome Location	17q25.3
Clonality	polyclonal
Description	Thymidine kinase 2 (TK2) salvages mitochondrial (mt) pyrimidine deoxynucleosides for mtDNA precursor synthesis. TK2 phosphorylates these nucleosides to their corresponding nucleoside monophosphates using a nucleotide triphosphate as a donor. Deficiency of mitochondrial TK2 manifests as severe skeletal myopathy during infancy, due to depletion of mtDNA. Mutant enzyme possesses similar K(m) values to wild type, however, the V(max) is markedly decreased, leading to the decreased enzyme efficiency, which causes the disease.
Host	Rabbit
Immunogen	Recombinant full length Human TK.
Reactivity	Human, Mouse, Rat
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P04183
Uniprot	P04183
Weight	25 kDa

Description	Product: 1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol. Specificity: TK polyclonal antibody detects endogenous levels of TK protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IF

Description

WB ; IF

Dilution

WB	1:500-1:2000
IF	1:50-1:200

Datasheet

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA11307474	BS7269	50µl	$234.89		Add to Cart
BHA11307474	BS7269	100µl	$368.22		Add to Cart

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