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Home / Primary Antibodies / IHC Antibodies

Anti-PRKCD Antibody BHA11302752

SKU : BHA11302752

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Mfr.No.	BS4861
Alternative Names	Protein kinase C delta type ; Tyrosine-protein kinase PRKCD ; nPKC-delta ; Sphingosine-dependent protein kinase-1 ; SDK1 ; PRKCD ; PKCδ
Categories	Primary Antibodies ; Phospho Antibodies
Chromosome Location	3p21.1
Clonality	polyclonal
Description	Protein Kinase C delta (PKC delta) is a 78 kDa member of the novel group (nPKCs: sensitive to diacylglycerol, phosphatidylserine, and phorbol esters) of the PKC family of serine/threonine kinases that are involved in a wide range of physiological processes including mitogenesis, cell survival and transcriptional regulation. PKC delta is an ubiquitously expressed PKC isozyme that has been implicated in the regulation of multiple cellular processes including cell cycle progression and apoptosis. Autophosphorylation of serine 664 (serine 662 in mouse and rat) contributes to PKC delta activity. Serum dependent phosphorylation of serine 664 is mediated by mTOR pathway, is protected from dephosphorylation by phosphorylated threonine 505 in the activation loop, and is implicated in prolactin signaling.
Host	Rabbit
Immunogen	Synthetic phosphopeptide derived from human PKC δ around the phosphorylation site of Tyrosine 52.
Modification	phospho-Y52
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	Q05655
Uniprot	Q05655
Weight	80 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2. Specificity: p-PKC δ (Y52) polyclonal antibody detects endogenous levels of PKC δ protein only when phosphorylated at Tyr52.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 97% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC

Description

WB ; IHC

Dilution

WB	1:500-1:1000
IHC	1:50-1:200

Datasheet

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA11302752	BS4861	50µl	$199.33		Add to Cart
BHA11302752	BS4861	100µl	$314.89		Add to Cart

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