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Home / Primary Antibodies / Phospho Antibodies

Anti-PFKFB2 Antibody BHA11302750

SKU : BHA11302750

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Mfr.No.	BS4859
Alternative Names	PFK-2 car ; PFK-2 cardiac ; 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 ; 6PF-2-K/Fru-2,6-P2ase 2 ; PFK/FBPase 2 ; 6PF-2-K/Fru-2,6-P2ase heart-type isozyme ; 6-phosphofructo-2-kinase ; Fructose-2,6-bisphosphatase ; PFKFB2
Categories	Primary Antibodies ; Phospho Antibodies
Chromosome Location	1q32.1
Clonality	polyclonal
Description	PFK-1 undergoes activation in the presence of elevated AMP. The most potent activator is fructose-2,6-bisphosphate, which is produced by PFK-2 from the same substrate, fructose 6-phosphate. PFK-2 is bifunctional and a key regulator for PFK-1. PFK-2 catalyzes the synthesis of fructose-2,6-bisphosphate, and contains fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. PFK-2 is dimeric and isoenzymes include PFK-2 liver (PFKFB1, PFRX), PFK-2 cardiac (PFKFB2), PFK-2 placental (PFKFB3, inducible PFK-2) and PFK-2 testis (PFKFB4).
Host	Rabbit
Immunogen	Synthetic phosphopeptide derived from human PFKFB2 around the phosphorylation site of Serine 483.
Modification	phospho-S483
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	O60825
Uniprot	O60825
Weight	58 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: p-PFKFB2 (S483) polyclonal antibody detects endogenous levels of PFKFB2 protein only when phosphorylated at Ser483.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC

Description

WB ; IHC

Dilution

WB	1:500-1:1000
IHC	1:50-1:200

Datasheet

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA11302750	BS4859	50µl	$199.33		Add to Cart
BHA11302750	BS4859	100µl	$314.89		Add to Cart

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