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Home / Primary Antibodies / IHC Antibodies

Anti-MTNR1B Antibody BHA11301609

SKU : BHA11301609

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Mfr.No.	BS2817
Alternative Names	Melatonin receptor type 1B ; Mel-1B-R ; Mel1b receptor ; MTNR1B
Categories	Primary Antibodies
Chromosome Location	11q14.3
Clonality	polyclonal
Description	The melatonin receptors, MEL-1A-R and MEL-1B-R, are members of the superfamily of guanine nucleotide-binding regulatory protein (G protein)-coupled receptors. The melatonin receptors are activated by the hormone melatonin (Mel), which is secreted by the pineal gland at night as part of the circadian clock. MEL-1A-R, a 37 kD protein, is thought to be involved in pacing the biological clock. However, both MEL-1A-R and MEL-1B-R are implicated in controlling cellular growth in response to melatonin. MEL-1B-R is an integral membrane protein expressed in retina and less in brain and hippocampus. Functional studies of NIH/3T3 cells stably expressing the MEL-1B-R melatonin receptor indicate that it is coupled to inhibition of adenylyl cyclase.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids N-terminus of Human MEL-1B-R.
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P49286
Uniprot	P49286
Weight	40 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: MEL-1B-R (V39) polyclonal antibody detects endogenous levels of MEL-1B-R protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

IHC

Description

IHC

Dilution

IHC	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11301609	BS2817	50µl	$190.44		Add to Cart
BHA11301609	BS2817	100µl	$294.44		Add to Cart

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