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Home / Primary Antibodies / IHC Antibodies

Anti-MEF2D Antibody BHA11302553

SKU : BHA11302553

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Mfr.No.	BS4326
Alternative Names	MEF2D,Myocyte-specific enhancer factor 2D
Categories	Primary Antibodies ; Phospho Antibodies
Chromosome Location	1q22
Clonality	polyclonal
Description	The myocyte enhancer factor-2 (MEF-2) family of transcription factors associate with co-repessors or co-activators to regulate development and function of T cells, neuronal cells, and muscle cells. Four family members arise from alternatively spliced transcripts, termed MEF-2A, -2B, -2C, and -2D. These members bind as homo- and heterodimers to the MEF-2 site in the promoter region of affected genes. Differential regulation in the expression of the four transcripts implies functional distinction for each duing embryogenesis and development. The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including MyoD, myogenin, Myf-5, and MRF4, are one class of identified factors. A second family of DNA binding regulatory proteins is the myocyte-specific enhancer factor-2 (MEF-2) family. Each of these proteins binds to the MEF-2 target DNA sequence present in the regulatory regions of many muscle-specific genes.
Host	Rabbit
Immunogen	Synthetic phosphopeptide derived from human MEF2D around the phosphorylation site of Serine 444.
Modification	phospho-S444
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	Q14814
Uniprot	Q14814
Weight	56 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: p-MEF2D (S444) polyclonal antibody detects endogenous levels of MEF2D protein only when phosphorylated at Ser444
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

IHC

Description

IHC

Dilution

IHC	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11302553	BS4326	50µl	$199.33		Add to Cart
BHA11302553	BS4326	100µl	$314.89		Add to Cart

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