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Home / Primary Antibodies / Phospho Antibodies

Anti-MAP2K4 Antibody BHA11302451

SKU : BHA11302451

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Mfr.No.	BS4167
Alternative Names	Dual specificity mitogen-activated protein kinase kinase 4 ; MAP kinase kinase 4 ; MAPKK 4 ; JNK-activating kinase 1 ; MAPK/ERK kinase 4 ; MEK 4 ; SAPK/ERK kinase 1 ; SEK1 ; Stress-activated protein kinase kinase 1 ; SAPK kinase 1 ; SAPKK-1 ; SAPKK1 ; c-Jun N-terminal kinase kinase 1 ; JNKK ; MAP2K4 ; JNKK1 ; MEK4 ; MKK4 ; PRKMK4 ; SEK1 ; SERK1 ; SKK1
Categories	Primary Antibodies ; Phospho Antibodies
Chromosome Location	17p12
Clonality	polyclonal
Description	The prototype member of this family, designated MAP kinase kinase, or MEK-1, specifically phosphorylates the MAP kinase regulatory threonine and tyrosine residues present in the Thr-Glu-Tyr motif of ERK. A second MEK family member, MEK-2, resembles MEK-1 in its substrate specificity. MEK-3 (or MKK-3) functions to activate p38 MAP kinase, and MEK-4 (also called SEK1 or MKK-4) activates both p38 and JNK MAP kinases. MEK-5 appears to specifically phosphorylate ERK 5, whereas MEK-6 phosphorylates p38 and p38β. MEK-7 (or MKK-7) phosphorylates and activates the JNK signal transduction pathway.
Host	Rabbit
Immunogen	Synthetic phosphopeptide derived from human MEK-4 around the phosphorylation site of Serine 80.
Modification	phospho-S80
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P45985
Uniprot	P45985
Weight	44 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: p-MEK-4/ MAP2K4 (S80) polyclonal antibody detects endogenous levels of MEK-4 protein only when phosphorylated at Ser80.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC

Description

WB ; IHC

Dilution

WB	1:500-1:1000
IHC	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11302451	BS4167	50µl	$199.33		Add to Cart
BHA11302451	BS4167	100µl	$314.89		Add to Cart

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