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Home / Primary Antibodies / IHC Antibodies

Anti-KRT18 Antibody BHA11300944

SKU : BHA11300944

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Mfr.No.	BS1833
Alternative Names	Keratin, type I cytoskeletal 18 ; Cell proliferation-inducing gene 46 protein ; Cytokeratin-18 ; Short name=CK-18 ; Keratin-18 ; Short name=K18 ; KRT18 ; CYK18 ; PIG46 ; KRT 18 ; CK 18 ; CK18 ; Keratin 18 ; Keratin18 ; CK-18
Categories	Primary Antibodies
Chromosome Location	12q13.13
Clonality	polyclonal
Description	Cytokeratin 18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.Involved in the uptake of thrombin-antithrombin complexes by hepatic cells By similarity. When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 21-70 of Human Cytokeratin 18.
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P05783
Uniprot	P05783
Weight	46 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: Cytokeratin 18 (S48) polyclonal antibody detects endogenous levels of Cytokeratin 18 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC, IF

Description

WB ; IHC ; IF

Dilution

WB	1:500-1:1000
IHC	1:50-1:200
IF	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11300944	BS1833	50µl	$190.44		Add to Cart
BHA11300944	BS1833	100µl	$294.44		Add to Cart

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