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Home / Primary Antibodies / IHC Antibodies

Anti-KRT16 Antibody BHA11300372

SKU : BHA11300372

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Mfr.No.	BS1202
Alternative Names	Keratin, type I cytoskeletal 16 ; Cytokeratin-16 ; Cytokeratin16 ; CK-16 ; CK16 ; Keratin-16 ; Keratin 16 ; Keratin16 ; Short name=K16 ; KRT16 ; KRT16A
Categories	Primary Antibodies
Chromosome Location	17q21.2
Clonality	polyclonal
Description	Keratin 16 is expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyperproliferation-related keratins). Keratin 16 is absent in normal breast tissue and in noninvasive breast carcinomas. Only 10% of the invasive breast carcinomas show diffuse or focal positivity. Reportedly, a relatively high concordance was found between the carcinomas immunostaining with the basal cell and the hyperproliferation-related keratins, but not between these markers and the proliferation marker Ki-67. This supports the conclusion that basal cells in breast cancer may show extensive proliferation, and that absence of Ki-67 staining does not mean that (tumor) cells are not proliferating
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 421-470 of Human Cytokeratin 16.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P08779
Uniprot	P08779
Weight	52 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: Cytokeratin 16 (S451) polyclonal antibody detects endogenous levels of Cytokeratin 16 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC

Description

WB ; IHC

Dilution

WB	1:500-1:1000
IHC	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11300372	BS1202	50µl	$190.44		Add to Cart
BHA11300372	BS1202	100µl	$294.44		Add to Cart

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